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Thursday, February 9, 2012

Myocardial Bridge

Myocardial Bridge-About Myocardial Bridge:

Myocardial bridge is a congenital vascular malformation. Cardiac contractility during coronary artery myocardial bridge cover are oppressed, there systolic stenosis, diastolic coronary oppression has been lifted, coronary artery stenosis have been relieved. 1960 postsmann and wig will first describe the muscle bridge in vivo angiography, mainly through angiography, see "systolic narrowing or milking effect" to identify its clinical significance has been debated.

Coronary artery and its branches are usually walking on the surface of the heart, epicardial fat or the epicardial deep surface, when the period of myocardial coronary artery was surrounded, the myocardium is known as a myocardial bridge, the segment of coronary artery known as the wall of coronaryartery. Myocardial bridge may be related to local factors and coronary heart disease may also cause myocardial ischemia.

1, the rate of myocardial bridge: Due to the different research methods, detection varies widely. Pathological series, its incidence vary widely, from 15% to 85%, while in the angiography series, the incidence rate of 051% to 25%. The Yetman such as that caused Both a large rate difference depends on several aspects: the length of the myocardial bridge, the accurate positioning of the left anterior descending artery bridge fiber, the relationship between myocardial bridge and the adjacent artery, the angiographic myocardial bridge not commensurate with the rate dependent on the length of the myocardial bridge, angiography is only aware of the deep muscle bridges, shallow muscle bridge when angiography is not easy to find. Report the application of nitroglycerin to increase the left anterior descending artery myocardial bridge systolic stenosis detection, thereby increasing the detection rate of myocardial bridge. Myocardial bridge detection rate in patients with hypertrophic cardiomyopathy patients, 30% to 50%, 28% of the incidence of children with hypertrophic cardiomyopathy, myocardial bridge. 7467 consecutive coronary angiography Juilliere and other reports, however, found that the myocardial bridge in 61 cases, 26 cases of coronary heart disease, four cases of heart valve disease, three cases of hypertrophic cardiomyopathy, and the remaining isolated myocardial bridge. Detected in patients with myocardial bridge, myocardial disease is not dominant.


Myocardial bridge with age, gender relations: myocardial bridge after birth, existence, development and adjacent arterial growth is closely related. Myocardial bridge in the rate of male slightly more than women, but there are also the authors suggest that no significant gender differences. Ferreira et al. Report for 90 cardiac autopsy findings, 50 heart myocardial bridge, including 32 males, 18 females, whose ages range from stillborn to 84 years, previously had no history of heart disease patients died of noncardiac disease caused by3, the location and number of myocardial bridge: myocardial bridge occurs most frequently in the left anterior descending artery, and located near the vessel, in 1/3, myocardial bridges can be a single can also be more occurrences of more occurrences of muscle bridge in the same vascular or coronary artery or their branches. Ferreira et al reported 50 myocardial bridge autopsy, 35 single muscle of the heart of the Department of the bridge, involving the left anterior descending artery, 10 the two muscles of the heart of the Department of bridge, heart, Department 3 5 muscle bridge. Juilliere such as detection of myocardial bridge in 7467 cases of coronary angiography, 61 cases are located in the left anterior descending artery. Also reported in the literature angiography cases of myocardial bridge in the right coronary artery.

Myocardial bridge - the cause of
Myocardial bridge is a relatively common congenital anatomic deformity. Cause of coronary artery myocardial segment, particularly within the segment of the left anterior descending artery myocardial systolic can be squeezed, and more symptoms of myocardial ischemia in middle age.

Myocardial bridge - pathogenesis
Myocardial bridge, myocardial bridge, myocardial fiber direction of the front descending artery and posterior descending artery at the vascular long axis nearly right angle before the right ventricular branch and left ventricular branch was at a slight angle.
Cross-section of the wall of coronary artery visible lumen is small, thin wall becomes more apparent when the myocardial bridge, thick wall of the coronary segments difficult to form atherosclerosis while its proximal and distal intimal you can often see atherosclerosis sclerosis.

Because of these anatomical features, when the contraction of the heart, myocardial bridge oppression mural coronary artery to lumen further narrow myocardial bridge the longer the thick myocardial fibers and blood vessels into the angle the greater the wall of coronary artery stenosis and the heavier the distal myocardial ischemia The more weight, or myocardial infarction.

Myocardial bridge - the pathophysiology of
Myocardial bridge, myocardial fiber direction of the front descending artery and posterior descending artery at the vascular long axis of the nearly right angle, before the right ventricular branch and left ventricular branch was at a slight angle. Cross-section of the wall of the coronary arteries visible lumen small, thin wall becomes more apparent when the thick of the myocardial bridge. The wall of the coronary segments difficult to form atherosclerosis, proximal and distal intimal atherosclerosis can frequently be seen. Because of these anatomical features, when the contraction of the heart, myocardial bridge oppression mural coronary artery, so that further narrow the lumen, and myocardial bridge is the longer, thicker, cardiac muscle fibers and blood vessels into the angle the greater the wall the more severe coronary artery stenosis, remote the more severe myocardial ischemia or myocardial infarction.

Myocardial bridge - clinical manifestations and significanceMyocardial bridge in the mural coronary artery muscle bridge coronary artery originating from the normal no abnormal channels and other congenital malformations and some heart to the adventitia of coronary artery proximal or middle of the shallow myocardial coverage by a short distance and then exposed to the outside of the myocardial myocardial coverage coronary segment called the mural coronary artery or coronary artery (intratunneledmajorcoronaryartery) pipeline, covering called shallow myocardium on the coronary muscle bridge.
Coronary artery wall can also be found on the left diagonal branch or left obtuse marginal branch of the mural coronary artery segments generally less prone to arterial atherosclerotic lesions, but the proximal wall of coronary atherosclerosis-prone due to the pressure within the lumen of proximal muscle bridge higher than normal intracoronary pressure and higher than the intra-aortic pressure on coronary angiography found that the mural coronary artery lumen in systole was significantly less than the diameter of the diastolic light in systolic, diastolic 60% to 70% weight by only 25%, or even complete occlusion of the Fuwai Hospital data show that 123 cases of the lumen of the mural coronary artery systolic luminal diastolic below 25% in 18 cases (14.6%), especially in patients with cardiac hypertrophy in systolic lumen compression. Systolic diameter less than 25% of the diastolic, the 201 sports thallium (201Tl) myocardial perfusion imaging and coronary sinus pacing metabolic product of myocardial ischemia in the majority of coronary perfusion with isolated systolic pressure and diastolic The reason may be caused by myocardial ischemia due to coronary artery wall tension or spasm some of symptomatic patients with coronary artery compression may be extended to early diastolic or with left ventricular hypertrophy in excessive myocardial oxygen consumption.
1, superficialCoronary blood flow due to myocardial bridge is thin and short small majority may be no symptoms of myocardial ischemia and ECG changes.2, depth-typeThat may occur due to myocardial bridge thick impact on coronary blood flow, and angina ECG myocardial ischemia, ST-T changes if the myocardial bridge concurrent coronary atherosclerosis secondary to thrombus formation or plaque off myocardial infarction symptoms and ECG changes of myocardial bridge merge Tachyarrhythmias are more vulnerable to myocardial ischemia.Previous studies that myocardial bridge is harmless at the clinical variability, and support for this view stems from the following observations: (1) myocardial bridge came into existence at birth, to produce clinical symptoms are often 30 to 40 years of age; (2) the oppression of the myocardial bridge occurred in the cardiac cycle of contraction late, due to higher peripheral vascular resistance, the physiological forward flow; (3) the extent of myocardial bridge angiography and clinical symptoms, exercise test or myocardial fluorescence when ischemic signs were not positive. However, recent angiography combined intravascular ultrasound study has the ability to prove that vascular compression of the myocardial bridge in systole, but continued to diastolic coronary flow reserve, which can reduce the myocardial bridge may cause myocardial ischemia, especially severe hemodynamic disorder patients.

Noble, etc. Review coronary angiography records for 5 years, 5250 cases, 27 cases of systolic left anterior descending artery myocardial bridge image, that is, milking the phenomenon, at the same time the coronary diameter in systolic over diastolic narrowing the degree is divided into three narrowing of 75% for grade Ⅲ, lactic acid significantly increased myocardial ischemic ECG changes, and certain clinical symptoms. Related to myocardial bridge cause many clinical cardiovascular events reported in the literature, can cause myocardial infarction, conduction block, arrhythmia, sudden death, myocardial stunning.