Filariasis is a parasitic disease caused by filarial parasites in the lymphoid tissue, subcutaneous tissue or cavity membrane cavity and cause serious damage to the body's lymphatic system, leading to recurrent inflammation, resulting in illness lose the ability to work.
Blood filariasis - Introduction
Blood filariasis filariasis is caused by parasites in the lymphoid tissue, subcutaneous tissue or cavity membrane cavity by the filarial parasites. Popular domestic lymphatic filariasis. Early clinical manifestations of lymphangitis and lymphadenitis, the late emergence of the symptoms of lymphatic obstruction. Blood microfilaria of patients or the parasite is the main source of infection, spread by mosquito bites, the crowd is generally susceptible to this disease is a Chinese "Falling Star", "Bigfoot Wind", "cream shower areas.
Blood filariasis is a mosquito-borne parasites and pathogens present in the animal body, not contagious from person to person. Blood filariasis would seriously undermine the body's lymphatic system, leading to recurrent inflammation, resulting in illness lose the ability to work.
Blood filariasis - effective treatment for drug
Ivermectin
Onchocerciasis with broad-spectrum anti-filarial activity of ivermectin, microfilaria of Onchocerca volvulus, dog filarial cotton rat filarial killing activity, but no adult activity. Can affect the normal development of the microfilaria of Onchocerca volvulus in the female womb, and to inhibit its release from the palace of pregnant insects to quickly reduce the number of microfilaria in the skin of patients, the first choice for treatment of onchocerciasis drugs, oral efficacy, but little for the adult role. Oral per kilogram of body weight 0.15-0.2mg, each interval of 6-12 months of retreatment, continued for several years. Diethylcarbamazine on Wuchereria bancrofti and Malayan filariasis while (sea Qunsheng) treatment may kill the microfilaria and adults on Wuchereria bancrofti, Brugia malayi, Emperor Wen Si insects and Ah-the filarial the giant silk larva has a considerable role in the body of filarial patients, make microfilaria disappeared rapidly from the blood. For Bancroftian filariasis, Malayan filariasis, in 600mg points on the 1st 2 times to give, after meals, for seven consecutive days for a course after the interval of 1-2 months, 2-3 courses; for the treatment of Ah filariasis 1 per kilogram of body weight 2-3mg three times a day for 2-3 weeks, if necessary after 3-4 weeks of retreatment; for onchocerciasis, the initial dose should be small, according to the weight 1 0.5mg, on the 1st to the 1 on the 2nd and the 3rd to 1 times 1mg, 1 three times, if no serious reactions can be increased to 1 2mg, 3 times a day, the total course on the 14th.
Blood filariasis - the clinical manifestations
A. Lymphoid tissue of acute inflammation
(1) acute lymphangitis, lymphadenitis: located in the lower limbs, showing the periodic episodes of high fever, chills.
(2) the filarial hot: was the periodic attacks of chills and fever.
(3) of the spermatic cord inflammation: epididymitis, orchitis, testicular, epididymal enlargement, tenderness, spermatic cord nodules, tenderness.
(4) pulmonary eosinophil syndrome: visible chills, fever, cough, asthma embolism.
Two. Lymphatic obstructive lesions: performance of the lymph nodes, varicose lymphatic vessels, and hydrocele, chyluria, elephantiasis, swelling (more common in lower limbs, scrotum and upper limbs), lymphatic ascites and chylous ascites.
Blood filariasis - Diagnostic
A. Endemic area of living history.
Two. Recurrent lymphadenitis, retrograde lymphangitis, chyluria, spermatic cord inflammation, elephantiasis, and can appear lymphoid ascites and chylous ascites.
3. Laboratory tests
(1) increase in blood: early leukocytes and eosinophils.
(2) immunological tests: complement fixation test, agar diffusion test and ELISA positive, helpful in the diagnosis.
(3) pathologic examination
① night from 10:00 to next day at 2:00 to take 3 drops of the ear lobe blood placed on the slide directly to find microfilaria.
The microfilaria ② chyluria, hydrocele Find.
③ lower extremity lymph node biopsy to find an adult.
4. The acute phase of lymphadenitis and lymphangitis should be noted that the identification of bacterial lymphadenitis.
