Alzheimer's disease

Alzheimer's disease-About Alzheimer's disease:

Alzheimer's disease, also known as Alzheimer'sdisease the AD and dementia in old age and early old primary degenerative encephalopathy, is a continuous movement disorder of higher nervous functions, namely, in the absence of awarenessbarriers to state, memory, thinking, analysis and judgment, as the space to identify emotional barriers. Their characteristic pathological changes of the cerebral cortex atrophy, accompanied by the beta-amyloid protein (beta-amyloid beta-AP) deposition, neurofibrillary tangles (neurofibrillarytangles NFT), reduced memory the number of neurons, as well as senile plaques (senileplaque SP) formation. There is no specific therapy for treatment or reversal of disease progression.

Alzheimer's disease - Disease Overview
Alzheimer's disease the so-called Alzheimer's disease, also known as Alzheimer's disease (Alzheimer'sdisease AD), occurs in old age and early old primary degenerative encephalopathy refers to is a continuous high-level the movement disorder of neurological function, namely the state of no disturbance of consciousness, memory, thinking, analysis and judgment of visual spatial recognition, and emotional barriers. Their characteristic pathological changes of the cerebral cortex atrophy, accompanied by the beta-amyloid protein (beta-amyloid beta-AP) deposition, neurofibrillary tangles (neurofibrillarytangles NFT), reduced memory the number of neurons, as well as senile plaques (senileplaque SP) formation. There is no specific therapy for treatment or reversal of disease progression. Is also one of the four common neurodegenerative diseases (the other three for Huntington's disease, Lou Gehrig's disease, Parkinson's disease).

The aging trend of increase in the number of elderly patients with dementia with the development of modern medicine, more and more elderly become young and full of vitality.

Decline in activities of daily living in Alzheimer's patients, they do not know your spouse, children, dressing, eating, bowel and bladder are not take care of themselves; some have auditory and visual hallucinations, endless pain and trouble to themselves and people around. Alzheimer's patients, the average survival period of 5.5 years, after, following cardiovascular disease, cerebrovascular disease and cancer, Alzheimer's disease, has become the health of the elderly "the fourth largest killer".

Dementia is not the elderly "patent" four or five years old on dementia, the number is also growing. Not just the elderly, 50-year-old daughter, accompanied by 80-year-old mother to see a doctor even both been diagnosed with Alzheimer's; 47-year-old woman forgetful, the same Alzheimer's to blame ... these are shows that age suffering from Alzheimer's in advance . Alzheimer's gradually getting younger and younger trend, the role of vascular factors in the pathogenesis of increasingly prominent.

In fact, Alzheimer's in middle age began to have symptoms and reactions, if not early detection and treatment, development of severe can not be cured. Dementia no longer the old "patent". The experts say that early dementia can be cured, you had better really can not be treated until the sixties and seventies.

Alzheimer's disease - the cause of disease
Alzheimer's disease - "amnesia" While the most common senile dementia also did not find the reasons, but all dementia symptoms follow, initial signs of memory loss. Into middle age, to see if you are not particularly fond of forget things? If you only occasionally forget but afterwards slowly recall, this is normal phenomenon. If you often forget things, and some things have to remember to forget also, would like to post up, and even affect the work and life, it is best to hospital to be checked.
Along with the "amnesia", there are some obvious signs, you may wish to give yourself to be a self-test below. Does not feel right, do not the parties, or afraid of being a joke, early symptoms can be cured, do not wait until confirmed again to rule.

(1) determine dementia systemic diseases.
(1) asked in detail about the medical history, medical history, conduct a comprehensive physical examination and routine laboratory tests.
② According to the the ① results obtained to identify or exclude targeted for further examination project.

(2) to determine the part of the dementia is a disease of nervous system
(1) asked in detail about the history, past history, and to conduct a comprehensive mental state, nervous system, physical examination and routine laboratory tests.
② ① the results need to identify or exclude nervous system diseases targeted for further examination, you can choose to check the following items:
Dynamic observation of the EEG, evoked potentials, a few 00, TCD, brain of MRI, SPECT, PET, cerebrospinal fluid and serum in the special biochemical tests such as tau protein, brain and peripheral nerve biopsy, histopathological, immunohistochemical and molecular biological examination.

Undo edits

Alzheimer's disease - etiological diagnosis(1) Alzheimer's disease
And vascular dementia lONINCDS the one ADHDA Alzheimer's disease diagnostic criteria: the points of possible Alzheimer's disease, Alzheimer's disease is likely, certainly Alzheimer's disease. .② the following contribute to the clinical diagnosis of AD: neuropsychological tests confirmed dementia; slow onset, gradually increased, without a history of stroke; neuropsychological impairments weight, mild neurological deficit; head of CT and MRI showed diffuse brain atrophy no focal lesions; Hackinski score less than 4 points; of SPECT shows bilateral Ying, top, occipital cortex blood flow symmetry to reduce. The final diagnosis still need to pathological examination.(2) and vascular dementia① determine dementia; must be accompanied by evidence of the risk of cerebrovascular disease (history, signs and imaging evidence); dementia and cerebrovascular disease, the two must be interrelated.② the following contribute to the clinical diagnosis of vascular dementia: a history of stroke and dementia; the signs and symptoms of neurological deficit; brain CT, MRI, the cerebral vascular damage manifested; Hachinski score> 7 points; of SPECT focal cerebral blood flow and reduce.
(3) mixed type dementiaMixed in dementia vascular dementia coexist with AD to determine whether the two disease exists, no doubt it is very difficult. The following points to help the clinical diagnosis: VD and AD both the clinical features of dementia course of the disease; brain CT, MRI, can cause dementia and cerebrovascular focal damage, moderate to severe leukoaraiosis and associated with diffuse brain atrophy . Finally Diagnosis was confirmed by pathological examination.
Alzheimer's disease - stage of the diseaseAlzheimer's disease is generally on Alzheimer's disease often occurs in the 50 years of age, onset hidden potential, the slow development of the earliest are often based on forgetfulness began gradually increased, if you do not pay attention, usually not easy to find, in accordance with the development of the disease can be broadly divided into three stages:The first phase, also known as the forgetfulness ofThis performance is significantly diminished memory, forget talked at the beginning, then, have done or important appointment, and slowly things even far forgotten. At the same time, thinking, analysis, judgment, depending on the spatial features, computing power has also been reduced, but sometimes it can also remain familiar in the past or skills.
The second stage, also known as a period of turmoilAt this time, in addition to the first phase of increased symptoms, a very outstanding performance as the space to identify barriers significantly worse, it is easy to get lost.There also very difficult to dress, or trousers, clothes; do not know the face of a friend or loved one, can not remember their names, can not talk to other people, sometimes talking to himself.
The third stage, also known as extreme dementia ofPatients were enrolled in full-blown recession, life can not take care of themselves, such as eating, dressing, bathing is required to take care of, they incontinence

 

Alzheimer's disease - symptoms of the diseaseAlzheimer's disease - the symptoms of dementia symptoms of dementia symptoms often occult, people pay attention to a correct understanding of dementia early symptoms so that patients receive timely treatment, delaying progress, it is very important.Dementia early performance of the memory impairment, the patient is easy to forget things, losing things, the initial presentation of forgetting the past things, such as the food just eaten a few hours before had been unable to recall. Sicker far things memory also affected, such as the inability to recall past experiences. Some patients showed affective disorder, early emotional instability, sentimental tears, failing to depression, depressed, as trivial anxious uneasy, afraid of fear. Some patients have cognitive impairments, the beginning can not concentrate, thoughts scattered, talk duplication, indecision is not resolved to form a sharp contrast with the previous competent. Some patients have mental disorders, memory loss, did not know where the things on, always suspected that someone had stolen his things. Some patients feel physical discomfort everywhere doctor to check, although not to detect abnormalities, but still feel the pain. Patients with sexual dysfunction, often suspected of spouse having an affair for this family is often noisy and Small number of patients with behavioral disorders, uncharacteristically parsimonious everywhere to collect waste, some patients simple sketches to paint himself as a famous painting, maintenance and the collection. Some patients to the new environment, often to the wrong house.
Memory deteriorates, affecting activities of daily livingSecond, deal with familiar things appear difficult, Time, place and character growing confusionFourth, the judgment gradually diminishOften what chaos on the inappropriateSix, abstract thinking problemsInstability and behavior of the seven emotional expression than before, was extremelyEight, character shiftsNine, lost the initiative to do things10, to understand things, capacity and language expression that difficulties
These early symptoms of non-simultaneous emergence of similar symptoms, should immediately go to hospital for psychological counseling, to make the necessary psychological testing and neurological examination, in order to facilitate early diagnosis.
Alzheimer's disease - treatment of diseaseFirst, the exercise therapy
Treatment of Alzheimer's disease (1) in place with fresh air every morning and evening brisk walking one hour: brisk walking can exercise the waist and lower part of the tense muscle, improve oxygen uptake, and help stimulate the brain cells to prevent the degradation of brain cells. prevention of Alzheimer's disease, the ideal performance.Often do the finger movements of the mind gymnastics: frequent hand fingers fingertip detailed activities such as arts and crafts, sculpture, drawing, paper cutting, typing, and playing a musical instrument with your fingers, make cerebral blood flow was extended to promote blood circulation, massage the brain, can help the brain and lively, and prevention of dementia.
The frequent use of the fingers and the ball or walnut, or with both hands to stretch the fist movement: finger brain is the most prominent part of the (Kant phrase). Often do exercise, can stimulate the brain cortex, and promote good blood circulation, enhance mental flexibility Alzheimer's disease, slow aging of brain cells, can prevent dementia.
(4) the implementation of the rotation movement around the head and neck: this movement not only allows the spine rotation becomes smooth, the prevention of elderly people suffering from the end of vertebral cerebral artery insufficiency disease, but also delayed cerebral arteriosclerosis, and prevention of Alzheimer's efficacy. The method is to first head and neck slowly from left to right rotation of 100 laps, and then rotation of the head and neck from right to left 100 laps, anywhere at any time to do

 

The Gastrodia treatment of Alzheimer's disease side
The Gastrodia formula: take Gastrodia 10 g porcine brain of a 250 grams of rice.Preparation method:1, the Gastrodia cut into very fine.2, panning clean wok with the of Gastrodia Suimo and porcine brain at the same time, add water, porridge, for the degree of brain cooked.Consumption method: daily morning take a times, even serving 2 to 7 days. One can always take it.The Gastrodia treatment of stroke sequelae sideRecipe: Gastrodia 10 g Scorpion 3 g.Preparation methods: a total of research to fine and uniform.Edible method: 2 grams per serving, heat the wine sent. 1 or 2 times a day. 30 days for a course of treatment and may even serve a two courseAlzheimer's is not only due to physiological causes, in fact, old age, lifestyle and loneliness lead to Alzheimer's, a healthy living environment to the elderly and the good life mentality is the best way to prevent Alzheimer's, hope everyone taking the time to spend time with elderly parents, do not let them feel lonely and alone.Alzheimer's disease - Disease PreventionPrevention due to the different causes of dementia, prevention methods, mainly the following aspects:To improve the working environment.2, avoid alcohol and smoking cessation.3, dietary modification: it is necessary to prevent high-fat foods cause elevated cholesterol, but also intake of essential nutrients, such as proteins, inorganic salts, amino acids and a variety of vitamins, especially vitamin B1, B2 and B6, vitamin C and vitamin E for the elderly is very important.4, to maintain a happy and conducive to longevity and mental health.To arrangements for living and learning: to old age, still insist on learning new knowledge, to maintain extensive contacts with the community.Retired before, in terms of ideology, material ready for anything, the rich content of life, a wide range of interests and hobbies, can promote mental activity, but also can delay or reduce the aging process., Regular medical examinations, early treatment of physical diseases, both should pay attention to their own bodies, not too much attention to or worry about.8, regular outdoor activities: the elderly suitable for more sustained than the sport, such as walking, jogging, gymnastics, tai chi, tai chi sword, and traditional dance.The treatment of AD are acetylcholinesterase (AchE) and anti-immune and inflammatory, anti-oxidants and other symptomatic therapy to temporarily relieve the patients with cognitive dysfunction.
Eat more bananas and apples can prevent Alzheimer's diseaseU.S. researchers to a new study, eat apples, bananas and oranges can help to reduce the risk of suffering from dementia.Cornell University researchers published in the latest issue of "Food Science" magazine reported that apples, bananas and oranges are the fruit of people's lives, not only rich in the human body needs vitamins, minerals and fiber , but also contains a type of antioxidant - phenol, has a protective effect on human brain cells.
The researchers found in the study of the role of three kinds of fruit juice on the nerve cells the phenol juice has antioxidant, can prevent the harmful substances and toxins into the nerve cells, which protect nerve cells from destruction.
Phenol up to three kinds of fruit, apples, bananas and oranges. Frequent eating of these three kinds of fruit in the diet useful for the prevention of Alzheimer's disease occurs.
Alzheimer's disease is a chronic problem affecting the health of the elderly. The information provided by the United States, "General Psychiatry", about 10 percent of the world's 60 years of age or older with the disease. According to the statistics of the World Health Organization and the International Association of Alzheimer's disease, more than 18 million elderly people suffering from Alzheimer's disease. Expected to 20 200 years, the global Alzheimer's patients will reach 34 million.
The study found that the diagnosis of "senile dementia" to start from the eye
U.S. researchers recently completed animal studies found that mice suffering from Alzheimer's disease, the retina will be similar to lesions of the brain. This means that might be able to more easily detected by the eye of early diagnosis and treatment of Alzheimer's disease.
Alzheimer's disease - Disease CareElderly patients with dementia at home, some are treated and cared for in hospitals and old age welfare institutions. So, how to care for before science?
First to prevent the elderly bedridden. Elderly patients with dementia, family members are often very easy to produce excessive protective tendencies, this is the biggest reason for the patient bedridden. Patients bedridden, there may be many complications, which will aggravate the symptoms of dementia to accelerate to shorten its life, so the early stage dementia patients should be allowed to do whatever their family care and guidance. In addition, family members should also understand the patient's mental state, must not alienate the patient, to help patients to exclude psychological disorders and behavioral disorders to help patients recover memories. This is a very important part in terms of prevention and treatment of patients with early,
Pay attention to diet and nutrition. Alzheimer's patients generally have different levels of eating disorders and swallowing disorders. Furthermore, the elderly, renal function and digestion and absorption dysfunction, reduced basal metabolism and decreased physical activity, reason, make the body use nutrients, absorb prone to disorder, leading to patient malnutrition, and even anemia. To consider the balance of quantity and quality of the diet of patients with dementia, you should use the easy to digest, easy to swallow food, protein, fat intake does not have to be limited. Low nutritional status, will further promote the development of the disease.
To maintain daily health habits. Of early dementia patients as possible to help keep the daily habits and health habits. Living, dressing, brushing teeth, wash, even doing non-standard, but also best to let him do it. This is also the link can not be ignored to prevent disease development. Bedridden patients must be given the care, cleaning the mouth, Give the patients a bath, shampoo, to wash clothes. Incontinence in patients with dementia often, in the event of incontinence, the condition has a very serious period. However, defecation, urination timely processing of clean, keep the skin clean and dry to prevent infection.
To prevent infection. The high incidence of dementia in patients with pneumonia, and mortality is also high. According to the foreign survey data reports, the cause of death in patients with dementia more than 90 percent of deaths due to pneumonia. Once the concurrent, rapid disease progression, especially in bedridden patients, the body function decline, such as respiratory function decline, the body's infection defense capabilities decline, as well as disturbance of consciousness, malnutrition, incontinence, bedsores Health, which is very easy to pneumonia. So as to avoid the occurrence of the above, once the concurrent infection should be treated.
To prevent bedsores. The so-called bed sores due to local circulation leaving the skin and subcutaneous tissue necrosis. Prevention of pressure sores occur, the first to bedridden patients, systemic and local administration. Body management, including treatment of the primary disease, improvement of general condition, body water and electrolyte balance, prevention of infection. Local management: bedridden patients 2-3 hours to transform a position to observe the skin, keep the skin clean, can not use alcohol, disinfectant cleaning with warm water. Local pad, pillows, foam-padded pillow hips, ribs and other good parts.

 

Alzheimer's disease - knowledge
Dementia syndrome, complications
Lung infection: lack of exercise in patients with dementia, weak immune system, prone to lung infections. Therefore, be especially careful to avoid the cold and prevent colds. Otherwise, the upper respiratory tract infection sputum difficult to expectorate easily down the respiratory tract spread to cause lung infection.(2) secondary to systemic infection: patients with dementia, such as prolonged bed rest and maintain a fixed position or posture for a long time, their body pressure areas are the back and lumbar back skin and soft tissue blood circulation is blocked, malnutrition, poor resistance resulting in local skin redness, ulceration and erosions, ulcers Duo formation of the serious decubitus ulcer expand deepen secondary systemic infection can cause sepsis and life-threatening.3 Urinary tract infections: patients with dementia syndrome, incontinence, such as timely processing of clean, easily lead to urinary tract infections. Should be noted that often replace the mattress, keeping the local cleaning, if the perianal skin redness can be used warm water scoured dry, and coated with zinc oxide paste, to protect the skin: If constipation should purge can be used enema or with soap and water enema. Diet to increase fiber intake to a certain extent, prevention of dry stool, traditional Chinese medicine senna flood damage on behalf of the tea with a good purge function.These points is a common complication of the dementia syndrome, in order to control the incidence of complications to the care of patients with dementia syndrome in their daily lives to pay special attention to make efforts to prevent the active treatment.
The difference between forgetfulness and dementiaForgetfulness is the weak performance of the elderly brain function, dementia pathological cerebral organic intelligence recession, how to distinguish between the two, the following reference:, Mood changes: forgetful elderly emotions; Dementia of the emotional world becomes the "madding crowd" and insensitive.The forgotten difference: always part of the forgetful elderly people have done things forgotten; dementia forgotten is malignant, can not remember what happened, it seems that this has entirely disappeared.Third, the ability of life: forgetful elderly will remember correctly, the date sometimes before speaking to forget, but they are still cooking their own lives, even to take care of the family; Dementia With sicker gradual loss of daily living.Fourth, the cognitive abilities: the forgetful elderly memory loss, but time, place, character relationships and the cognitive ability of the surrounding environment did not reduced; dementia for the elderly it is devoid of the identification of the cognitive ability of the surrounding environment, can not distinguish on the afternoon I do not know the seasonal changes, I do not know where you are, and sometimes even find my way home.Thinking change: forgetful elderly on memory decline very upset, in order not to mess things up, often remember the memo; Dementia no trouble thinking more and more dull, speech is increasingly scarce, the lack of a sense of humor, the slow response. Whether, humor and colorful language, is one of the important symbol of the difference between physiological forgetfulness and dementia.
Eat yuba can prevent Alzheimer'sYuba the brain, it can prevent the occurrence of Alzheimer's disease. This is because the the yuba high glutamate levels in 2 to 5 times of the other legumes or animal food, glutamate plays an important role in brain activity. In addition, the phospholipids contained in the yuba can reduce blood cholesterol levels, to prevent the effect of hyperlipidemia, arteriosclerosis; soybean saponin, anti-inflammatory, anti-ulcer role.Yuba's nutritional value is high, but some people, such as nephritis, renal dysfunction, the best eating, otherwise they will be worse.
Control diet can alleviate Alzheimer'sUniversity of Southern California and University of Florida researchers found that the control diet to alleviate Alzheimer's symptoms in mice. This conclusion is only against the cage of mice derived can be applied to the human need for more evidence.In the experiment, the researchers used genetically engineered mice. Implanted in their body's genes, taken from two hereditary Alzheimer's disease of the human family. These adolescent mice were divided into two groups, one group can be free to eat, while the other group in the four weeks 40% of the reduction of food intake. Subsequently, the researchers observed that the amyloid plaques in the two groups of mice brain tissue.The researchers found that, forced to go on a diet of mice, 50% of the number and size of amyloid plaques are the other group. On the accumulation of amyloid plaques in the brain tissue of Alzheimer's disease patients, especially in the hippocampus and frontal cortex accumulation of amyloid plaques, are thought to cause the culprit of the patients with loss of memory.The researchers said the experiment proved the diet can alleviate Alzheimer's symptoms, and the same mutated gene from two different family, the next step they will need to study why this effect is so obvious and far-reaching. They believe that the diet reduces glucose and insulin levels in mice, this may be the direction of the research.
Prevention of Alzheimer's, eat the lilyLily has a significant role in reducing animal serum cholesterol, and therefore, it is the prevention of high blood cholesterol and slow the aging body, Vegetable. In addition, the lily of the high nutritional value. Hectogram containing protein 14.1 g, calcium 463 mg, 173 mg of phosphorus, as well as a variety of vitamins, especially carotene, the most abundant. Lily to stop bleeding, anti-inflammatory, diuretic, stomachic, sedative. Flowers, stems, leaves, roots can be used as medicine. Its root end stew or stewed chicken, the treatment of anemia, senile and dizziness, with good results. But pay attention to the lily must be stored after cooking dried, and then eat.